Polyethylene Glycol 400 (PEG 400) is a low-molecular-weight, water-soluble polymer widely used across multiple industries. With its excellent solubility, lubricating properties, and non-toxic nature, PEG 400 is an essential ingredient in pharmaceutical, cosmetic, and industrial formulations.
Applications
1. Pharmaceutical Industry
PEG 400 is widely utilized as an excipient in drug formulations due to its biocompatibility and solubility.
Uses:
- Carrier for liquid and semi-solid drug formulations
- Base for topical ointments and creams
- Solubilizer and stabilizer for APIs
Benefits:
- Improves drug delivery and solubility
- Provides consistency in formulations
- Safe for oral, topical, and parenteral applications
2. Cosmetics and Personal Care
In cosmetics, PEG 400 enhances the texture, stability, and performance of products.
Uses:
- Humectant and emollient in skincare and haircare products
- Solvent for fragrances and essential oils
- Base for creams, lotions, and gels
Benefits:
- Moisturizes and conditions the skin and hair
- Improves product spreadability and consistency
- Non-irritating and skin-friendly
3. Industrial Applications
PEG 400 plays a critical role in various industrial processes.
Uses:
- Lubricant in machinery and metalworking
- Solvent in paints, coatings, and inks
- Dispersing agent in adhesives and sealants
Benefits:
- Enhances material properties and processing efficiency
- Compatible with a wide range of chemicals
- Provides smooth and uniform performance
4. Food and Beverage Industry
As a food-grade polymer, PEG 400 is used in food processing applications.
Uses:
- Solvent for food flavorings and additives
- Lubricant for food machinery
Benefits:
- Recognized as safe (GRAS) for specific applications
- Non-toxic and easily metabolized
Safety and Handling
Safety Precautions
Although PEG 400 is considered safe, handling it with care is essential to prevent exposure-related issues.
- Personal Protective Equipment (PPE): Wear gloves and goggles when handling.
- Avoid Inhalation: Use in well-ventilated areas to avoid inhaling vapors.
- Minimize Contact: Avoid prolonged skin or eye contact.
First Aid Measures
- Skin Contact: Wash thoroughly with soap and water. Seek medical advice if irritation occurs.
- Eye Contact: Flush with water for at least 15 minutes. Consult a healthcare professional if irritation persists.
- Inhalation: Move to fresh air. Seek medical attention if symptoms develop.
- Ingestion: Rinse mouth and drink water. Contact a physician if adverse effects are observed.
Storage Guidelines
- Store in a cool, dry place, away from direct sunlight.
- Keep containers tightly sealed to prevent contamination.
- Avoid contact with strong oxidizers.
Environmental Considerations
PEG 400 is biodegradable and environmentally friendly when used appropriately. Avoid large-scale release into waterways or soil.
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