SODIUM BOROHYDRIDE

Sodium Borohydride (NaBH₄) is a highly effective reducing agent widely used in chemical synthesis, water treatment, and various industrial processes. It is a white crystalline solid, soluble in water and lower alcohols. Known for its ability to selectively reduce aldehydes, ketones, and other compounds, Sodium Borohydride is a key reagent in organic and pharmaceutical chemistry.

Applications

1. Pharmaceutical Industry

• Chemical Synthesis: Used in the production of active pharmaceutical ingredients (APIs) through reduction reactions.
• Intermediate Reduction: Converts ketones, aldehydes, and other functional groups into alcohols during drug synthesis.

2. Organic Chemistry

• Reducing Agent: Selectively reduces aldehydes, ketones, and esters to their corresponding alcohols without affecting other functional groups.
• Synthesis of Complex Molecules: Plays a crucial role in the creation of alcohols and other derivatives for research and industrial purposes.

3. Pulp and Paper Industry

• Bleaching Agent: Reduces residual lignin in paper pulp to improve brightness and whiteness.

4. Water Treatment

• Pollutant Removal: Acts as a reducing agent to neutralize heavy metals, chlorinated compounds, and other contaminants in wastewater.

5. Fuel and Energy Sector

• Hydrogen Storage and Generation: Used as a hydrogen source in portable fuel cells and energy applications.

6. Laboratory Applications

• Analytical Reagent: Employed in various analytical procedures for chemical transformations and research.

Safety and Handling

Hazards:

• Flammability: Reacts with water and acids to release flammable hydrogen gas.
• Skin and Eye Irritation: Can cause burns or irritation upon contact.
• Toxicity: Harmful if swallowed, inhaled, or absorbed through the skin.

Precautions:

• Personal Protective Equipment (PPE):
  • Wear gloves, protective eyewear, and lab coats.
  • Use in a well-ventilated area or under a fume hood.
• Handling Guidelines:
  • Avoid contact with water or moisture to prevent hydrogen release.
  • Store under dry, inert conditions (e.g., in a nitrogen or argon atmosphere).
• Storage:
  • Keep in a tightly sealed container away from moisture and incompatible substances like acids or oxidizers.

First Aid Measures:

• Inhalation: Move to fresh air immediately. Seek medical attention if symptoms persist.
• Skin Contact: Wash thoroughly with soap and water. Seek medical assistance for severe exposure.
• Eye Contact: Rinse with water for 15 minutes, holding eyelids open. Get medical help immediately.
• Ingestion: Do not induce vomiting. Rinse mouth and seek emergency medical care.

Disposal:

Dispose of Sodium Borohydride in compliance with local environmental regulations. Avoid uncontrolled release into water systems.