PROPYL GALLATE

Propyl gallate (C₁₁H₁₄O₅) is an ester of gallic acid and propanol. It is a white to off-white crystalline powder that is commonly used as an antioxidant in various industries. As a highly effective preservative, propyl gallate helps to prevent the oxidation of oils, fats, and other sensitive substances, extending their shelf life. It is commonly found in the food, cosmetic, and pharmaceutical industries for its ability to inhibit the degradation of products caused by oxidative damage.

Applications

1. Food Industry
   • Antioxidant and Preservative:
     Propyl gallate is commonly used in the food industry to prevent the oxidation of oils, fats, and processed foods. It helps preserve the color, flavor, and nutritional value of products, particularly in items like vegetable oils, margarine, and fried snacks.
   • Emulsions and Dairy Products:
     It is used in dairy products and emulsions to prevent rancidity and extend shelf life, maintaining the quality and taste of products.
2. Cosmetic and Personal Care
   • Preservative in Skincare Products:
     Propyl gallate is used in cosmetic formulations such as creams, lotions, and sunscreens to prevent the degradation of oils and protect the product from oxidative spoilage.
   • Antioxidant in Cosmetics:
     It is included in formulations to help maintain the integrity of active ingredients and prevent the product from losing efficacy due to oxidation.
3. Pharmaceuticals
   • Preservative in Medicinal Formulations:
     In the pharmaceutical industry, propyl gallate is used as an antioxidant in formulations of medications, particularly in liquid oral solutions and injectable products. It prevents the degradation of sensitive ingredients and extends the shelf life of pharmaceuticals.
   • Stabilizer for Active Ingredients:
     Propyl gallate helps stabilize active ingredients, particularly in vitamin-based and other sensitive drug products.
4. Animal Feed and Pet Food
   • Preservative in Animal Feed:
     Propyl gallate is sometimes added to animal feed to preserve fats and oils, preventing rancidity and ensuring the nutritional value of feed remains intact.
5. Chemical Industry
   • Antioxidant in Polymers:
     It is used in the manufacturing of plastics and polymers as an antioxidant to prevent degradation of materials caused by oxygen exposure, particularly in products exposed to sunlight.
   • Lubricants and Greases:
     In industrial applications, propyl gallate is utilized as an antioxidant in lubricants and greases to ensure stability and prevent oxidation.
6. Textile Industry
   • Antioxidant in Textile Dyes:
     It is employed in textile dye formulations to prevent oxidative degradation of dyes and improve the shelf life and quality of textile products.

Safety and Handling

• Hazards:
  • Propyl gallate is generally considered safe for use in low concentrations in food and cosmetic products. However, exposure to high concentrations can cause irritation to the skin, eyes, and respiratory tract.
  • It is classified as a mild irritant to the eyes and skin, and prolonged exposure may cause sensitization or allergic reactions in some individuals.
• Precautions:
  • Personal Protective Equipment (PPE): When handling propyl gallate in large quantities, wear appropriate protective gloves, goggles, and clothing to avoid skin or eye contact.
  • Ventilation: Ensure proper ventilation when working with propyl gallate in confined spaces, especially in powdered form, to avoid inhaling dust.
  • Storage: Store in a cool, dry place away from sources of heat or flame. Ensure containers are tightly sealed to prevent contamination.
• First Aid:
  • Eye Contact: Immediately flush eyes with water for at least 15 minutes. Seek medical attention if irritation persists.
  • Skin Contact: Wash affected skin with soap and water. If irritation or redness occurs, seek medical advice.
  • Inhalation: Move to fresh air immediately. If symptoms like dizziness, coughing, or difficulty breathing occur, seek medical attention.
  • Ingestion: If swallowed, rinse mouth with water and seek medical attention. Do not induce vomiting unless directed by a medical professional.